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1

Lentinan: Hematopoietic, Immunological, and Efficacy Studies in a Syngeneic Model of Acute Myeloid Leukemia

McCormack, Emmet, Skavland, Jørn, Mujić, Maja, Bruserud, Øystein, Gjertsen, Bjørn Tore

Journal:

Nutrition and Cancer

Year:

2010

Language:

english

File:

PDF, 348 KB

english, 2010

2

Expression profile of heat shock proteins in acute myeloid leukaemia patients reveals a distinct signature strongly associated with FLT3 mutation status – consequences and potentials for pharmacological intervention

Håkon Reikvam, Kimberley J. Hatfield, Elisabeth Ersvær, Randi Hovland, Jørn Skavland, Bjørn T. Gjertsen, Kjell Petersen, Øystein Bruserud

Journal:

British Journal of Haematology

Year:

2012

Language:

english

File:

PDF, 556 KB

english, 2012

3

Increased antileukemic effects in human acute myeloid leukemia by combining HSP70 and HSP90 inhibitors

Reikvam, Håkon, Nepstad, Ina, Sulen, André, Gjertsen, Bjørn Tore, Hatfield, Kimberley Joanne, Bruserud, Øystein

Journal:

Expert Opinion on Investigational Drugs

Year:

2013

Language:

english

File:

PDF, 719 KB

english, 2013

4

Heat shock protein 70 – the next chaperone to target in the treatment of human acute myelogenous leukemia?

Reikvam, Håkon, Brenner, Annette K, Nepstad, Ina, Sulen, André, Bruserud, Øystein

Journal:

Expert Opinion on Therapeutic Targets

Year:

2014

Language:

english

File:

PDF, 635 KB

english, 2014

5

Targeting mitochondria in the treatment of human cancer: a coordinated attack against cancer cell energy metabolism and signalling

Hagland, Hanne, Nikolaisen, Julie, Hodneland, Linn I, Gjertsen, Bjøorn T, Bruserud, Øystein, Tronstad, Karl J

Journal:

Expert Opinion on Therapeutic Targets

Year:

2007

Language:

english

File:

PDF, 233 KB

english, 2007

6

Modified fatty acids and their possible therapeutic targets in malignant diseases

Tronstad, Karl J, Berge, Kjetil, Berge, Rolf Kristian, Bruserud, Øystein

Journal:

Expert Opinion on Therapeutic Targets

Year:

2003

Language:

english

File:

PDF, 245 KB

english, 2003

7

How should quality of life assessment be integrated in the evaluation of patients with acute myeloid leukemia?

Tvedt, Tor Henrik Anderson, Reikvam, Håkon, Aasebø, Elise, Hernandez-Valladares, Maria, Berven, Frode S., Selheim, Frode, Bruserud, Øystein

Journal:

Expert Review of Quality of Life in Cancer Care

Year:

2016

Language:

english

File:

PDF, 1.27 MB

english, 2016

8

Splenic tyrosine kinase (SYK) inhibitors and their possible use in acute myeloid leukemia

Bartaula-Brevik, Sushma, Lindstad Brattås, Marte Karen, Tvedt, Tor Henrik Anderson, Reikvam, Håkon, Bruserud, Øystein

Journal:

Expert Opinion on Investigational Drugs

Year:

2018

Language:

english

File:

PDF, 1.11 MB

english, 2018

9

Preservation Method and Phosphate Buffered Saline Washing Affect the Acute Myeloid Leukemia Proteome

Wangen, Rebecca, Aasebø, Elise, Trentani, Andrea, Døskeland, Stein-Ove, Bruserud, Øystein, Selheim, Frode, Hernandez-Valladares, Maria

Journal:

International Journal of Molecular Sciences

Year:

2018

Language:

english

File:

PDF, 1.79 MB

english, 2018

10

Disease-stabilizing treatment with all-trans retinoic acid and valproic acid in acute myeloid leukemia: Serum hsp70 and hsp90 levels and serum cytokine profiles are determined by the disease, patient age, and anti-leukemic treatment

Hanne Fredly, Håkon Reikvam, Bjørn Tore Gjertsen, Øystein Bruserud

Journal:

American Journal of Hematology

Year:

2012

Language:

english

File:

PDF, 1.14 MB

english, 2012

11

CD34 expression in native human acute myelogenous leukemia blasts: Differences in CD34 membrane molecule expression are associated with different gene expression profiles

Anne Margrete Øyan, Trond Hellem Bø, Inge Jonassen, Elling Ulvestad, Bjørn Tore Gjertsen, Karl-Henning Kalland, Øystein Bruserud

Journal:

Cytometry Part B: Clinical Cytometry

Year:

2005

Language:

english

File:

PDF, 922 KB

english, 2005

12

Serum levels of angiogenin, basic fibroblast growth factor and endostatin in patients receiving intensive chemotherapy for acute myelogenous leukemia

Nils Glenjen, Knut Anders Mosevoll, Øystein Bruserud

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 204 KB

english, 2002

13

Effects of cytarabine and various anthracyclins on platelet activation: Characterization of in vitro effects and their possible clinical relevance in acute myelogenous leukemia

Brynjar Foss, Elling Ulvestad, Tor Hervig, Øystein Bruserud

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 134 KB

english, 2002

14

In vitro effects of native human acute myelogenous leukemia blasts on fibroblasts and osteoblasts

Nils Glenjen, Elisabeth Ersvær, Anita Ryningen, Øystein Bruserud

Journal:

International Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 141 KB

english, 2004

15

Microvascular endothelial cells increase proliferation and inhibit apoptosis of native human acute myelogenous leukemia blasts

Kimberley Hatfield, Anita Ryningen, Matthias Corbascio, Øystein Bruserud

Journal:

International Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 325 KB

english, 2006

16

CD4+TCRαβ+ T-cells developing after allogeneic bone marrow transplantation in patients with chronic myelogenous leukaemia. Dipyridamole inhibits functionally heterogeneous T-cell clones

Øystein Bruserud, Wilfried Hamann, Sarita Patel, Graham Pawelec

Journal:

International Journal of Immunopharmacology

Year:

1991

Language:

english

File:

PDF, 610 KB

english, 1991

17

CD4+ TCRαβ+ T-cell clones derived shortly after allogeneic bone marrow transplantation: Theophyllamine and verapamil inhibit proliferation of functionally heterogeneous T-cells

Øystein Bruserud, Wilfried Hamann, Sarita Patel, Graham Pawelec

Journal:

International Journal of Immunopharmacology

Year:

1992

Language:

english

File:

PDF, 536 KB

english, 1992

18

Comparison of nucleic acid targets prepared from total RNA or poly(A) RNA for DNA oligonucleotide microarray hybridization

Kjell Petersen, Anne Margrete Øyan, Kari Rostad, Sue Olsen, Trond Hellem Bø, Helga B. Salvesen, Bjørn Tore Gjertsen, Øystein Bruserud, Ole Johan Halvorsen, Lars Andreas Akslen, Vidar M. Steen, Inge Jo

Journal:

Analytical Biochemistry

Year:

2007

Language:

english

File:

PDF, 731 KB

english, 2007

19

Current practice and future directions for optimization of platelet transfusions in patients with severe therapy-induced cytopenia

Torunn O. Apelseth, Tor Hervig, Øystein Bruserud

Journal:

Year:

2011

Language:

english

File:

PDF, 190 KB

english, 2011

20

Untangling the intracellular signalling network in cancer — A strategy for data integration in acute myeloid leukaemia

Katarina M. Jørgensen, Sigrun M. Hjelle, Ola K. Øye, Pål Puntervoll, Håkon Reikvam, Jørn Skavland, Endre Anderssen, Øystein Bruserud, Bjørn Tore Gjertsen

Journal:

Journal of Proteomics

Year:

2011

Language:

english

File:

PDF, 1.03 MB

english, 2011

21

Cellular immune responses in multiple myeloma patients with treatment-induced cytopenia early after high-dose chemotherapy and autologous peripheral blood stem cell transplantation

Øystein Wendelbo, Ingerid Nesthus, Malvin Sjo, Peter Ernst, Øystein Bruserud

Journal:

Leukemia Research

Year:

2004

Language:

english

File:

PDF, 106 KB

english, 2004

22

In vitro crosstalk between fibroblasts and native human acute myelogenous leukemia (AML) blasts via local cytokine networks results in increased proliferation and decreased apoptosis of AML cells as well as increased levels of proangiogenic Interleukin 8

Anita Ryningen, Line Wergeland, Nils Glenjen, Bjørn Tore Gjertsen, Øystein Bruserud

Journal:

Leukemia Research

Year:

2005

Language:

english

File:

PDF, 248 KB

english, 2005

23

Stress-induced in vitro apoptosis of native human acute myelogenous leukemia (AML) cells shows a wide variation between patients and is associated with low BCL-2:Bax ratio and low levels of heat shock protein 70 and 90

Anita Ryningen, Elisabeth Ersvær, Anne Margrete Øyan, Karl-Henning Kalland, Olav Karsten Vintermyr, Bjørn Tore Gjertsen, Øystein Bruserud

Journal:

Leukemia Research

Year:

2006

Language:

english

File:

PDF, 863 KB

english, 2006

24

Clonogenic acute myelogenous leukemia cells are heterogeneous with regard to regulation of differentiation and effect of epigenetic pharmacological targeting

Anita Ryningen, Camilla Stapnes, Øystein Bruserud

Journal:

Leukemia Research

Year:

2007

Language:

english

File:

PDF, 1.10 MB

english, 2007

25

A subset of patients with high-risk acute myelogenous leukemia shows improved peripheral blood cell counts when treated with the combination of valproic acid, theophylline and all-trans retinoic acid

Anita Ryningen, Camilla Stapnes, Philippe Lassalle, Matthias Corbascio, Bjørn-Tore Gjertsen, Øystein Bruserud

Journal:

Leukemia Research

Year:

2009

Language:

english

File:

PDF, 662 KB

english, 2009

26

Heat shock protein 90 (HSP90) inhibition—From experimental to clinical studies

Øystein Bruserud, Håkon Reikvam

Journal:

Leukemia Research

Year:

2010

Language:

english

File:

PDF, 99 KB

english, 2010

27

In vitro culture of human acute lymphoblastic leukemia (ALL) cells in serum-free media; a comparison of native ALL blasts, ALL cell lines and virus-transformed B cell lines

Øystein Bruserud, Nils Glenjen, Anita Ryningen, Elling Ulvestad

Journal:

Leukemia Research

Year:

2003

Language:

english

File:

PDF, 108 KB

english, 2003

28

Peripheral blood progenitor cell grafts contain high levels of platelet-secreted mediators

Brynjar Foss, Jenny Foss Abrahamsen, Øystein Bruserud

Journal:

Transfusion (Wiley)

Year:

2001

Language:

english

File:

PDF, 154 KB

english, 2001

29

Cryopreserving human peripheral blood progenitor cells with 5-percent rather than 10-percent DMSO results in less apoptosis and necrosis in CD34+ cells

Jenny Foss Abrahamsen, Anne M. Bakken, Øystein Bruserud

Journal:

Transfusion (Wiley)

Year:

2002

Language:

english

File:

PDF, 305 KB

english, 2002

30

Intensive chemotherapy for acute myeloid leukemia differentially affects circulating TC1, TH1, TH17 and TREGcells

Elisabeth Ersvaer, Knut Liseth, Jørn Skavland, Bjørn Tore Gjertsen, Øystein Bruserud

Journal:

Year:

2010

Language:

english

File:

PDF, 2.57 MB

english, 2010

31

In vitro effect of r-verapamil on acute myelogenous leukemia blast cells: studies of cytokine secretion and cytokine-dependent blast proliferation

Øystein Bruserud, Ingrid Nesthus, Graham Pawelec

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1995

Language:

english

File:

PDF, 811 KB

english, 1995

32

Human acute lymphoblastic leukemia (ALL) blasts as accessory cells during T-cell activation: differences between patients in costimulatory capacity affect proliferative responsiveness and cytokine release by activated T cells

Øystein Bruserud, Elling Ulvestad

Journal:

Cancer Immunology, Immunotherapy

Year:

2003

Language:

english

File:

PDF, 360 KB

english, 2003

33

How should clinical data be included in experimental studies of cancer immunology?

Bjørn Tore Gjertsen, Øystein Bruserud

Journal:

Cancer Immunology, Immunotherapy

Year:

2004

Language:

english

File:

PDF, 127 KB

english, 2004

34

Functional characterization of T lymphocytes derived from patients with acute myelogenous leukemia and chemotherapy-induced leukopenia

Øystein Wendelbo, Ingerid Nesthus, Malvin Sjo, Kristin Paulsen, Peter Ernst, Øystein Bruserud

Journal:

Cancer Immunology, Immunotherapy

Year:

2004

Language:

english

File:

PDF, 230 KB

english, 2004

35

Is targeted chemotherapy an alternative to immunotherapy in chronic lymphocytic leukemia?

Øystein Bruserud, Karl Johan Tronstad, Emmet McCormack, Bjørn Tore Gjertsen

Journal:

Cancer Immunology, Immunotherapy

Year:

2006

Language:

english

File:

PDF, 256 KB

english, 2006

36

Immunotherapy in chronic lymphocytic leukemia

Øystein Bruserud, Emmet McCormack, Bjørn Tore Gjertsen

Journal:

Cancer Immunology, Immunotherapy

Year:

2006

Language:

english

File:

PDF, 135 KB

english, 2006

37

T lymphocyte chemotactic chemokines in acute myelogenous leukemia (AML): local release by native human AML blasts and systemic levels of CXCL10 (IP-10), CCL5 (RANTES) and CCL17 (TARC)

Astrid Marta Olsnes, Dmitri Motorin, Anita Ryningen, Andrey Y. Zaritskey, Øystein Bruserud

Journal:

Cancer Immunology, Immunotherapy

Year:

2006

Language:

english

File:

PDF, 293 KB

english, 2006

38

Effects of interferon gamma on native human acute myelogenous leukaemia cells

Elisabeth Ersvaer, Jørn Skavland, Elling Ulvestad, Bjørn Tore Gjertsen, Øystein Bruserud

Journal:

Cancer Immunology, Immunotherapy

Year:

2007

Language:

english

File:

PDF, 355 KB

english, 2007

39

T cells remaining after intensive chemotherapy for acute myelogenous leukemia show a broad cytokine release profile including high levels of interferon-γ that can be further increased by a novel protein kinase C agonist PEP005

Elisabeth Ersvær, Peter Hampson, Kimberley Hatfield, Elling Ulvestad, Øystein Wendelbo, Janet M. Lord, Bjørn Tore Gjertsen, Øystein Bruserud

Journal:

Cancer Immunology, Immunotherapy

Year:

2007

Language:

english

File:

PDF, 482 KB

english, 2007

40

Future perspectives: should Th17 cells be considered as a possible therapeutic target in acute myeloid leukemia patients receiving allogeneic stem cell transplantation?

Elisabeth Ersvær, Guro Kristin Melve, Øystein Bruserud

Journal:

Cancer Immunology, Immunotherapy

Year:

2011

Language:

english

File:

PDF, 331 KB

english, 2011

41

Soluble Fas/Apo-1 (CD95) levels during T cell activation in the presence of acute myelogenous leukemia accessory cells; contributions from local release and variations in systemic levels

Øystein Bruserud, Elling Ulvestad

Journal:

Cancer Immunology, Immunotherapy

Year:

2000

Language:

english

File:

PDF, 173 KB

english, 2000

42

Human T lymphocyte activation in the presence of acute myelogenous leukaemia blasts: studies of allostimulated interferon-γ secretion

Øystein Bruserud, Laila Mentzoni, Brynjar Foss, Jann Bergheim, Sigbjørn Berentsen, Ingerid Nesthus

Journal:

Cancer Immunology, Immunotherapy

Year:

1997

Language:

english

File:

PDF, 174 KB

english, 1997

43

Interleukin-13 secretion by normal and posttransplant T lymphocytes; in vitro studies of cellular immune responses in the presence of acute leukaemia blast cells

Øystein Bruserud, Graham Pawelec

Journal:

Cancer Immunology, Immunotherapy

Year:

1997

Language:

english

File:

PDF, 837 KB

english, 1997

44

Cellular immune responses in acute leukaemia patients with severe chemotherapy-induced leucopenia; characterization of the cytokine repertoire of clonogenic T cells

Øystein Bruserud

Journal:

Cancer Immunology, Immunotherapy

Year:

1998

Language:

english

File:

PDF, 215 KB

english, 1998

45

In vitro effects of R-verapamil on the cytokine environment and T-lymphocyte proliferation when human T-lymphocyte activation takes place in the presence of acute myelogenous leukemia blasts

Øystein Bruserud

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1996

Language:

english

File:

PDF, 210 KB

english, 1996

46

In vitro culture of human osteosarcoma cell lines: a comparison of functional characteristics for cell lines cultured in medium without and with fetal calf serum

Øystein Bruserud, Karl Johan Tronstad, Rolf Berge

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2005

Language:

english

File:

PDF, 302 KB

english, 2005

47

The proteasome inhibitors bortezomib and PR-171 have antiproliferative and proapoptotic effects on primary human acute myeloid leukaemia cells

Camilla Stapnes, Anne P. Døskeland, Kimberley Hatfield, Elisabeth Ersvær, Anita Ryningen, James B. Lorens, Bjørn Tore Gjertsen, Øystein Bruserud

Journal:

British Journal of Haematology

Year:

2007

Language:

english

File:

PDF, 853 KB

english, 2007

48

Primary human acute myeloid leukaemia cells increase the proliferation of microvascular endothelial cells through the release of soluble mediators

Kimberley Hatfield, Anne M. Øyan, Elisabeth Ersvaer, Karl-Henning Kalland, Philippe Lassalle, Bjørn T. Gjertsen, Øystein Bruserud

Journal:

British Journal of Haematology

Year:

2009

Language:

english

File:

PDF, 401 KB

english, 2009

49

The protein kinase C agonist PEP005 increases NF-κB expression, induces differentiation and increases constitutive chemokine release by primary acute myeloid leukaemia cells

Astrid Marta Olsnes, Elisabeth Ersvær, Anita Ryningen, Kristin Paulsen, Peter Hampson, Janet M. Lord, Bjørn Tore Gjertsen, Einar Klæboe Kristoffersen, Øystein Bruserud

Journal:

British Journal of Haematology

Year:

2009

Language:

english

File:

PDF, 390 KB

english, 2009

50

Better preservation of early hematopoietic progenitor cells when human peripheral blood progenitor cells are cryopreserved with 5 percent dimethylsulfoxide instead of 10 percent dimethylsulfoxide

Jenny Foss Abrahamsen, Leiv Rusten, Anne M. Bakken, Øystein Bruserud

Journal:

Transfusion (Wiley)

Year:

2004

Language:

english

File:

PDF, 101 KB

english, 2004

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